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KMID : 0378119820090010107
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Chungnam Medical Journal
1982 Volume.9 No. 1 p.107 ~ p.111
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Relationship of Phytohemagglutinin Skin Test to the Clinical and Histopathological Types of Leprosy
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Abstract
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This study was undertaken to evaluate the histopathological findings of phytohemagglutinin(PHA) skin reaction after intradermal injection of 2 mg of PHA in the patients with leprosy.
The histopathologic findings of PHA skin reaction revealed that perivascular and periappendegeal mononuclear cell infiltration in mild inflammatory cases. In severe inflammatory cases, there were marked vasodilatation, edema and extravasations of erythrocytes in dermis and mononuclear cell infiltration admixed with many eosinophils and neutrophils around the dermal vessels, epidermal appendages and between the dermal collagen bundles. There was no difference in histopathologic findings of PHA skin reaction according to the clinical and histopathological types of leprosy.
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